Fig. 8. The inhibition of autophagy decreases the expression of DDX53 and enhances the sensitivity to anti-cancer drugs.

(A) MDA-MB-231 cells were treated with CQ (50 μM) for 24 h, followed by Western blot analysis. (B) MDA-MB-231 cells were treated with CQ (50μM) for 24 h. After removal of CQ, cells were then treated with or without the indicated anti-cancer drug for 24 h. MDA-MB-231 cells untreated with CQ were also treated with the indicated anti-cancer drug for 24 h. MTT assays were carried out. **p < 0.005. (C) Same as B except that Western blot analysis was carried out.