Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 13;8:22. doi: 10.3389/fpsyt.2017.00022

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Ferguson, Petty, Rohrscheib, Troup, Kirszenblat, Eyles and van Swinderen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Transient 23E10-Gal4 driven knockdown of D1 receptors during development increases daytime sleep intensity in adult flies. (A) Daytime (left) and nighttime (right) sleep intensity (% reaction proportion ± SEM) of treated C5-Gal4/UAS-Dop1R1; tubulin (tub)-Gal80TS animals (light gray, N = 56) and C5-Gal4/UAS-Dop1R2; tub-Gal80TS (dark gray, N = 34) compared to C5-Gal4/+ (black, N = 108) and RNAi (UAS-Dop1R1; tub-Gal80TS/+, N = 81, not shown) genetic controls. (B) % reaction proportion (±SEM) of treated 23E10-Gal4/UAS-Dop1R1; tub-Gal80TS animals (light gray, N = 81), and 23E10-Gal4/UAS-Dop1R2; tub-Gal80TS (dark gray, N = 66) during the day (left) and night (right) compared to 23E10-Gal4/+ (black, N = 159). *P < 0.05, **P < 0.01, decreased% reaction proportion compared to both genetic controls, by one-way ANOVA, adjusted for multiple comparisons by a Post Hoc Tukey’s test. (C) % reaction proportion (±SEM) of treated 201y-Gal4/UAS-Dop1R1; tub-Gal80TS animals (white, N = 56) and 201y-Gal4/UAS-Dop1R2; tub-Gal80TS (dark gray, N = 30) compared to 201y-Gal4/+ (black, N = 41) and RNAi (UAS-Dop1R2; tub-Gal80TS/+, N = 32, not shown) genetic controls.