Table 2. Comparison of AUROC to predict 3-month, 6-month and 1-year post-transplant mortality between MELD and other formulas in different etiologies.
| HBV (n = 4,436) | HCV (n = 509) | Alcohol (n = 314) | ||||
|---|---|---|---|---|---|---|
| AUROC (95% CI) | P * | AUROC (95% CI) | P * | AUROC (95% CI) | P * | |
| 3- month | ||||||
| MELD | 0.704 (0.669–0.742) | 0.665 (0.554–0.775) | 0.635 (0.473–0.796) | |||
| uMELD | 0.704 (0.667–0.740) | 0.729 | 0.659 (0.541–0.776) | 0.718 | 0.646 (0.469–0.822) | 0.912 |
| MELD-Na | 0.700 (0.663–0.737) | 0.207 | 0.654 (0.539–0.770) | 0.718 | 0.643 (0.504–0.783) | 0.912 |
| iMELD | 0.679 (0.642–0.717) | 0.004 | 0.649 (0.528–0.770) | 0.718 | 0.629 (0.493–0.766) | 0.912 |
| UKELD | 0.647 (0.606–0.687) | <0.001 | 0.607 (0.478–0.735) | 0.516 | 0.610 (0.471–0.747) | 0.912 |
| MELD-AS | 0.701 (0.665–0.738) | 0.636 | 0.622 (0.501–0.744) | 0.620 | 0.630 (0.480–0.779) | 0.912 |
| CTP | 0.630 (0.592–0.668) | <0.001 | 0.621 (0.505–0.738) | 0.718 | 0.599 (0.412–0.786) | 0.912 |
| mCTP | 0.646 (0.608–0.684) | <0.001 | 0.607 (0.488–0.726) | 0.718 | 0.622 (0.441–0.803) | 0.912 |
| 6- month | ||||||
| MELD | 0.690 (0.655–0.726) | 0.641 (0.532–0.751) | 0.603 (0.441–0.792) | |||
| uMELD | 0.688 (0.653–0.724) | 0.720 | 0.641 (0.527–0.756) | 0.998 | 0.621 (0.449–0.792) | 0.975 |
| MELD-Na | 0.685 (0.649–0.720) | 0.210 | 0.627 (0.511–0.742) | 0.998 | 0.611 (0.466–0.755) | 0.975 |
| iMELD | 0.665 (0.630–0.701) | 0.024 | 0.628 (0.512–0.745) | 0.998 | 0.595 (0.454–0.738) | 0.975 |
| UKELD | 0.638 (0.600–0.676) | <0.001 | 0.587 (0.463–0.710) | 0.476 | 0.593 (0.460–0.726) | 0.975 |
| MELD-AS | 0.686 (0.651–0.721) | 0.646 | 0.600 (0.485–0.715) | 0.636 | 0.602 (0.453–0.752) | 0.975 |
| CTP | 0.622 (0.586–0.658) | <0.001 | 0.606 (0.499–0.714) | 0.998 | 0.588 (0.412–0.764) | 0.975 |
| mCTP | 0.639 (0.603–0.674) | <0.001 | 0.614 (0.506–0.722) | 0.998 | 0.639 (0.467–0.810) | 0.975 |
| 1- year | ||||||
| MELD | 0.679 (0.644–0.714) | 0.640 (0.534–0.745) | 0.590 (0.43645–0.7) | |||
| uMELD | 0.676 (0.641–0.711) | 0.630 | 0.635 (0.525–0.745) | 0.812 | 0.603 (0.438–0.767) | 1.000 |
| MELD-Na | 0.675 (0.640–0.710) | 0.519 | 0.623 (0.513–0.734) | 0.804 | 0.593 (0.453–0.733) | 1.000 |
| iMELD | 0.660 (0.625–0.695) | 0.104 | 0.632 (0.523–0.732) | 0.812 | 0.573 (0.433–0.713) | 1.000 |
| UKELD | 0.631 (0.594–0.669) | <0.001 | 0.577 (0.460–0.693) | 0.330 | 0.553 (0.409–0.698) | 1.000 |
| MELD-AS | 0.677 (0.642–0.712) | 0.630 | 0.593 (0.480–0.706) | 0.330 | 0.591 (0.448–0.733) | 1.000 |
| CTP | 0.611 (0.575–0.646) | <0.001 | 0.604 (0.502–0.706) | 0.812 | 0.555 (0.378–0.731) | 1.000 |
| mCTP | 0.627 (0.591–0.662) | <0.001 | 0.599 (0.491–0.707) | 0.812 | 0.605 (0.432–0.777) | 1.000 |
*: vs. MELD
Comparison of AUROCs was adjusted by Hommel correction.
AUROC, area under the receiver operating characteristic curve; MELD, model for end-stage liver disease; HBV, hepatitis B virus; HCV, hepatitis C virus; UKELD, United Kingdom MELD; MELD-Na, MELD-sodium; iMELD, integrated MELD; CTP, Child-Turcotte-Pugh; uMELD, updated MELD; mCTP, modified Child-Turcotte-Pugh.