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. 2017 Feb 10;10(2):229–240. doi: 10.1016/j.tranon.2016.12.011

Figure 5.

Figure 5

Flow cytometry of C6 and U87 cell apoptosis with 4- and 8-Gy radiation. (A) Cells were exposed to 4-Gy irradiation. A total of 100 μg/ml of nanoparticles caused increases in the apoptosis compared to the VPA group. A total of 100 μg/ml of nanoparticles treatment increased the apoptotic rate of C6, and in pH 6 conditions, the apoptotic rate was higher than in normal PH conditions. (B) Apoptotic rate was further increased with exposure to 8-Gy irradiation. (C and D). Histograms show changes of the apoptotic rate. With 4- and 8-Gy radiation, significant changes were observed in PH6 VPA-MSNs group compared with the VPA group or the control (*P < .05, **P < .01).