Table 1.
Sciatic Function Nerve Index (SFI) at various intervention periods | |||||||||
---|---|---|---|---|---|---|---|---|---|
Group | Baseline | 1 day | 3 days | 6 days | 9 days | 12 days | 15 days | 18 days | 21 days |
DM + crush injury + no treatment | −8.42 ± 1.23 | −93.3 ± 0.00 | −93.3 ± 0.00 | −93.3 ± 0.00 | −93.30 ± 0.00 | −70.01 ± 2.70 | −62.84 ± 8.78 | −57.50 ± 2.74 | −37.75 ± 6.65 |
DM + crush injury + zein based nanofiber | −3.33 ± 6.64 | −93.3 ± 0.00 | −93.3 ± 0.01 | −93.3 ± 0.01 | −67.53 ± 5.86∗∗∗ | −63.27 ± 9.46∗ | −53.31 ± 6.32 | −44.94 ± 4.62 | −16.87 ± 1.58∗∗∗ |
DM + crush injury + 5% quercetin | −4.68 ± 7.14 | −93.3 ± 0.00 | −93.3 ± 0.02 | −93.3 ± 0.02 | −56.30 ± 2.07∗∗∗,## | −53.66 ± 9.39∗∗ | −31.49 ± 6.02∗∗∗,## | −23.53 ± 4.22∗,# | −9.11 ± 4.66∗∗∗ |
DM + crush injury + 10% quercetin | −4.94 ± 3.90 | −93.3 ± 0.00 | −93.3 ± 0.03 | −93.3 ± 0.03 | −61.69 ± 2.98∗∗∗ | −56.59 ± 13.17∗∗ | −26.59 ± 3.61∗∗∗,## | −24.78 ± 3.55∗∗∗,### | −9.16 ± 1.18∗∗∗,## |
DM + crush injury + 15% quercetin | −8.73 ± 1.13 | −93.3 ± 0.00 | −93.3 ± 0.04 | −93.3 ± 0.04 | −93.30 ± 0.00 | −78.59 ± 9.11 | −30.04 ± 7.64∗∗∗,## | −26.18 ± 6.45∗∗∗,### | −8.36 ± 1.26∗∗∗,### |