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. 2017 Jan 30;2017:2017493. doi: 10.1155/2017/2017493

Table 1.

The effect of zein-based polymeric nanofibers loaded with quercetin on the lesioned nerve function in diabetic rats (n = 8/group). The SFI are regarded as normal when they fall within the range of −10 to 10%. p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001, respectively, compared to DM + crush injury and no treatment. #p < 0.05 and ##p < 0.01, respectively, compared to DM + crush injury + zein-based nanofiber.

Sciatic Function Nerve Index (SFI) at various intervention periods
Group Baseline 1 day 3 days 6 days 9 days 12 days 15 days 18 days 21 days
DM + crush injury + no treatment −8.42 ± 1.23 −93.3 ± 0.00 −93.3 ± 0.00 −93.3 ± 0.00 −93.30 ± 0.00 −70.01 ± 2.70 −62.84 ± 8.78 −57.50 ± 2.74 −37.75 ± 6.65
DM + crush injury + zein based nanofiber −3.33 ± 6.64 −93.3 ± 0.00 −93.3 ± 0.01 −93.3 ± 0.01 −67.53 ± 5.86∗∗∗ −63.27 ± 9.46 −53.31 ± 6.32 −44.94 ± 4.62 −16.87 ± 1.58∗∗∗
DM + crush injury + 5% quercetin −4.68 ± 7.14 −93.3 ± 0.00 −93.3 ± 0.02 −93.3 ± 0.02 −56.30 ± 2.07∗∗∗,## −53.66 ± 9.39∗∗ −31.49 ± 6.02∗∗∗,## −23.53 ± 4.22,# −9.11 ± 4.66∗∗∗
DM + crush injury + 10% quercetin −4.94 ± 3.90 −93.3 ± 0.00 −93.3 ± 0.03 −93.3 ± 0.03 −61.69 ± 2.98∗∗∗ −56.59 ± 13.17∗∗ −26.59 ± 3.61∗∗∗,## −24.78 ± 3.55∗∗∗,### −9.16 ± 1.18∗∗∗,##
DM + crush injury + 15% quercetin −8.73 ± 1.13 −93.3 ± 0.00 −93.3 ± 0.04 −93.3 ± 0.04 −93.30 ± 0.00 −78.59 ± 9.11 −30.04 ± 7.64∗∗∗,## −26.18 ± 6.45∗∗∗,### −8.36 ± 1.26∗∗∗,###