Table 3.

The effect of the zein-based polymeric nanofibers loaded with quercetin on the oxidative stress status of the lesioned nerve in diabetic rats (n = 8/group). ^∗p < 0.05, ^∗∗p < 0.01, and ^∗∗∗p < 0.001, respectively, compared to DM + crush injury and no treatment. ^#p < 0.05, ^##p < 0.01, and ^###p < 0.001, respectively, compared to DM + crush injury + zein-based nanofiber.

Group	MDA level	SOD activity	CAT activity	GPx activity
	(nmol/min·g. protein)	(u/mg. protein)	(u/mg. protein)	(u/mg. protein)
DM + crush injury + no treatment	0.02 ± 0.005	3.22 ± 0.023	9.87 ± 1.83	9.69 ± 1.17
DM + crush injury + zein-based nanofibers	0.02 ± 0.004	2.75 ± 0.32	7.72 ± 1.24	6.62 ± 1.12
DM + crush injury + 5% quercetin	0.01 ± 0.002∗∗##	11.77 ± 2.47#	21.55 ± 5.23∗#	24.51 ± 4.12∗∗∗#
DM + crush injury + 10% quercetin	0.01 ± 0.001∗#	23.80 ± 2.82∗∗∗###	23.82 ± 5.56∗#	24.16 ± 5.09∗∗#
DM + crush injury + 15% quercetin	0.00 ± 0.000	5.00 ± 0.94	19.74 ± 3.16∗##	18.22 ± 3.06∗#