Table 4.

2006 Versus 2015 direct ophthalmic medical costs and patient value gain versus ranibizumab therapy for first two years

Cost	2006	2015
Physician	$6167 (11.7%)	$2611 (5.6%)
Ranibizumab	$44,812 (85.2%)	$42,665 (91.9%)
Diagnostic tests	$1230 (2.3%)	$1174 (2.5%)
Post-operative antibiotics	$414 (0.8%)	$0 (0.0%)
Total	$52,652 (100%)	$46,450 (100%)
Adjusted with medical CPI to 2015 US $	$70,161	$46,450
Decrease in real dollars from 2006 to 2015	NA	−33.8%
Patient value (quality-of-life) gain	2006	2015
First-eye model	6.4%	9.8%
Second-eye model	15.8%	22.8%
Combined-eye model	10.4%	16.3%

Parentheses indicate percent of total direct ophthalmic medical costs. NA not applicable. Note that patient value gain = quality-of-life gain