Table 3.

Multivariate Cox regression analysis

Disease-free survival	HR	95% CI	p value
Number of positive nodes
≥4 versus 1–3	2.51	1.88–3.63	<0.001
Tumor size
2–5 cm versus ≤2 cm	1.45	1.08–1.95	0.013
>5 cm versus ≤2 cm	1.65	1.10–2.48	0.015
Adjuvant HT
Yes versus no	0.69	0.51–0.93	0.016
OPN mRNA expression
High versus low	1.34	1.04–1.71	0.022
Overall survival
Number of positive nodes
≥4 versus 1–3	3.59	2.48–5.19	<0.001
Tumor size
2–5 cm versus ≤2 cm	1.59	1.13–2.34	0.009
>5 cm versus ≤2 cm	1.87	1.18–2.97	0.008
Adjuvant HT
Yes versus no	0.55	0.39–0.76	<0.001
OPN mRNA expression
High versus low	1.54	1.16–2.05	0.003

HR hazard ratio, CI confidence interval