Fig. 3.
Medial-to-lateral soma size gradient in the MNTB is absent in dfw2J mutants. A: cells were defined as medial if located in the medial third of the MNTB or lateral if located in the lateral third of the MNTB. B: there was a significant increase in the size of lateral cells compared with medial cells in the wild-type animals (*P ≤ 0.001). There was no significant increase in the size of lateral cells in +/dfw2J, dfw/dfw, dfw2J/dfw2J, or DTR mice. Error bars show SE. C: individual average cell size for medial and lateral cells in each MNTB. D: scatterplot of location along the tonotopic axis vs. cross-sectional surface area for 1 MNTB from a wild-type and a dfw2J/dfw2J mouse. The linear regression is significantly different from zero for wild type (P = 0.01) but not for dfw2J/dfw2J.