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. 2014 Apr 23;4(2):319–330. doi: 10.3390/nano4020319

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Images of HeLa cells in the presence of PEI-coated MNPs or MNP/antibody complexes and the application of an AC magnetic field for 1 h. Cell conditions and magnetic field intensities were: (b) PEI-coated MNPs and 210 Oe; (c) PEI-coated MNPs and 250 Oe; (d) complexes and 210 Oe; and (e) complexes and 250 Oe. The image in (a) is of the control cells in Figure 7. The AC magnetic field frequency was 210 kHz. The clusters in (c) and (e) are cell colonies. Cells had adhered and formed large colonies in (a), (b) and (d). However, cells were divided into a number of small colonies in (c) and (e).