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. 2014 Aug 20;4(3):741–765. doi: 10.3390/nano4030741

Table 3.

Amphiphilic cyclodextrins derivatives and their potential application fields.

Amphiphilic CDs Systems Potential applications Refs.
Heptakis (2-O-oligo(ethyleneoxide)-6-hexadecylthio-)-β-CD (SC16OH) Nanoparticles Drug carriers (docetaxel) [58]
6-O-CAPRO-β-CD Nanoparticles (nanospheres, nanocapsules, vesicles) Drug carriers (paclitaxel, camptothecin) [59,60]
βCD-C6/6-N-CAPRO-β-CD 6-N-MYRISTO-β-CD Nanospheres Nanocapsules Drug carriers (progesterone, camptothecin) [35,36,60]
Oligoethyleneimine-βCD CDplexes Gene delivery [61]
Heptakis[6-(2-amino-ethylthio)-6-deoxy-2-O-octylsulfanylpropyl]-β-cyclodextrin hepta-N-trifluoroacetate CDplexes Gene delivery [62]
Heptakis[6-diBoc-guanidinoethylthio-2-O-(N-(ω-(p-methoxybenzamido)-PEG440-yl)-1′H-triazole-4’-yl-methyl)]-β-cyclodextrin CDplexes Gene delivery [63]
Heptakis[6-deoxy-6-(2-(N’-(2-(N,N-di-(2-aminoethyl)amino)ethyl)thioureido)ethylthio)-2,3-di-O-hexanoyl] cyclomaltoheptaose CDplexes Gene delivery [64]
Heptakis(6-dodecylthio-2-oligo(ethylenoxide)-β-cyclodextrin-2-(4-(phenyldiazenyl)phenoxy) acetate Vesicles Phototherapy [65]
Heptakis(2-O-oligo(ethylene oxide)-6-hexylthio)-β-CD (SC6OH) Nanoparticles Phototherapy [30]
SC6NH3-β-CD; SC16NH3-β-CD Multilayer films Photoresponsive multilayer films [66]
Peptidyl-β-cyclodextrins Assemblies with biological membranes Artificial receptors [67]
Amphiphilic β-cyclodextrins with n-dodecyl groups and n-hexadecyl chains on both faces Assemblies with biological membranes Artificial receptors [28]