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. 2015 Dec 11;5(4):2231–2248. doi: 10.3390/nano5042231

Figure 2.

Figure 2

After disrupting the blood-brain barrier (BBB), nanoparticles (NPs) can accumulate at the tumor site. Receptor-mediated endocytosis of the functionalized NPs by cells overexpressing a receptor can retain NPs inside the tumor.