TABLE 2.
Mean (SE) change in assessment outcome at weeks 7 and 14.
| Measure | Mean (SE) change at 7 wks
|
Mean (SE) change at 14 wks
|
||
|---|---|---|---|---|
| MPACT (n = 11) | Control (n = 7) | MPACT (n = 11) | Control (n = 7) | |
| Physical performance | ||||
| Knee extension strength, N-m | 1 (11) | −36 (16)* | −4 (7) | −46 (14)† |
| 6-min walk distance, feet | −71 (36) | −166 (93) | 60 (40) | −19 (89) |
| Comfortable gait speed, m/s | −0.08 (0.04) | −0.14 (0.09) | 0.02 (0.04) | −0.05 (0.06) |
| Timed up and go (s) | 0.7 (0.8) | −0.07 (0.7) | −0.7 (0.6) | −0.2 (0.6) |
| Quality of life and sleep | ||||
| Overall SF-36 | −19 (5) | −24 (5) | 4 (4) | −6 (8) |
| SF-36 physical summary | −24 (6) | −22 (8) | 1 (4) | −3 (8) |
| SF-36 mental summary | −12 (7) | −26 (6) | 9 (4) | −9 (12) |
| SF-36 subscale: vitality | −19 (7) | −33 (3)* | 7 (5) | −9 (10) |
| SF-36 subscale: mental health | 3 (4) | −16 (7)* | 15 (4) | −1 (6)† |
| MOS sleep index | −5 (5) | 8 (6) | −14 (5) | −1 (11) |
| BMI and lean body mass | ||||
| BMI | −2.9 (0.6) | −3 (0.5) | −3.9 (0.7) | −4.6 (0.6) |
| Lean body mass, percent | 0.2 (0.5) | 1.0 (0.7) | 4.7 (1.5) | 4.0 (0.9) |
| Self-reported physical activity | ||||
| PASE | −65 (24) | −96 (35) | 42 (18) | −10 (31) |
| Objective physical activity | (n = 4) | (n = 3) | (n = 4) | (n = 3) |
| Proportion of lifestyle min | −0.03 (0.01) | −0.07 (0.03) | 0.00 (0.01) | −0.03 (0.01) |
| Proportion of sedentary min | 0.04 (0.02) | 0.08 (0.02) | −0.02 (0.02) | 0.06 (0.03) |
| No. of sit-to-stand transitions | 11.5 (7.9) | −2.7 (5.2) | 6.7 (8.9) | 1.8 (2.1) |
Abbreviations: MPACT, maintain physical activity during cancer treatment; N-m, Newton-meter; m/s, meters/second; SF-36, Short Form Health Survey; MOS, Medical Outcomes Study; BMI, body mass index; PASE, Physical Activity Scale for the Elderly.
*
Refers to p < .05 when comparing MPACT vs controls from baseline to 7-weeks.
†
Refers to p < .05 when comparing MPACT vs controls from baseline to 14-weeks.