Table 4.
Odds ratios and 95% confidence intervals for 2nd trimester levels of phthalate metabolites in quartiles and impaired glucose tolerance
| Impaired Glucose Tolerance1 | ||
|---|---|---|
| Phthalate metabolites |
Unadjusted | Multivariable2 |
| MEP | ||
| Q1 | Ref | Ref |
| Q2 | 1.93 (0.61, 6.09) | 2.14 (0.57, 8.10) |
| Q3 | 2.18 (0.70, 6.77) | 2.53 (0.71, 8.97) |
| Q4 | 3.59 (1.22, 10.55) | 7.18 (1.97, 26.15) |
| p for trend | 0.02 | <0.01 |
| MBP | ||
| Q1 | Ref | Ref |
| Q2 | 1.00 (0.37, 2.70) | 0.95 (0.31, 2.91) |
| Q3 | 1.13 (0.43, 2.99) | 1.26 (0.43, 3.68) |
| Q4 | 1.27 (0.49, 3.29) | 1.14 (0.37, 3.51) |
| p for trend | 0.58 | 0.74 |
| MiBP | ||
| Q1 | Ref | Ref |
| Q2 | 0.46 (0.15, 1.43) | 0.47 (0.14, 1.58) |
| Q3 | 0.77 (0.28, 2.10) | 1.16 (0.38, 3.54) |
| Q4 | 1.79 (0.75, 4.31) | 1.79 (0.62, 5.16) |
| p for trend | 0.1 | 0.18 |
| MBzP | ||
| Q1 | Ref | Ref |
| Q2 | 1.13 (0.43, 2.99) | 1.17 (0.40, 3.48) |
| Q3 | 1.13 (0.43, 2.99) | 1.16 (0.39, 3.49) |
| Q4 | 1.13 (0.43, 2.99) | 1.28 (0.40, 4.07) |
| p for trend | 0.82 | 0.69 |
| MCPP | ||
| Q1 | Ref | Ref |
| Q2 | 0.57 (0.21, 1.58) | 0.47 (0.14, 1.52) |
| Q3 | 0.88 (0.34, 2.23) | 0.97 (0.34, 2.77) |
| Q4 | 0.98 (0.39, 2.45) | 0.96 (0.34, 2.71) |
| p for trend1 | 0.76 | 0.7 |
| ∑DEHP | ||
| Q1 | Ref | Ref |
| Q2 | 0.64 (0.25, 1.63) | 0.46 (0.15, 1.40) |
| Q3 | 0.73 (0.29, 1.80) | 0.74 (0.27, 2.04) |
| Q4 | 0.48 (0.18, 1.30) | 0.25 (0.08, 0.85) |
| p for trend | 0.2 | 0.06 |
1
Defined as GLT>140mg/dL from 50-gram, non-fasting glucose load tests as first step in Carpenter-Coustan GDM screening test
2
Adjusted for age, race/ethnicity, education baseline BMI, alcohol drinking, and smoking