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. 2017 Feb 7;12:1047–1064. doi: 10.2147/IJN.S115215

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© 2017 Gao et al. This work is published and licensed by Dove Medical Press Limited

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Characterization of the micelles.

Notes: (A) Representative particle size distribution of DOX-loaded mixed micelles (HD micelles/DOX) obtained by DLS analysis. (B) A typical TEM image of DOX-loaded HD micelles. The scale bar is 1 μm. CMC of (C) the PHIS-PEG₂₀₀₀ micelle and (D) the HD micelle.

Abbreviations: DOX, doxorubicin; DLS, dynamic light scattering; TEM, transmission electron microscope; CMC, critical micelle concentration; PHIS-PEG₂₀₀₀, poly(l-histidine)-coupled polyethylene glycol-2000; HD micelles, PHIS-PEG₂₀₀₀ and DSPE-PEG₂₀₀₀ hybrid micelle; DSPE-PEG₂₀₀₀, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol-2000.