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. Author manuscript; available in PMC: 2017 Feb 13.
Published in final edited form as: Science. 2016 Aug 25;353(6306):1387–1393. doi: 10.1126/science.aaf5211

Fig. 3.

Fig. 3

GII.4 variants and GII.3 HuNoVs replicate in HIEs generated from different intestinal segments. Duodenal (D1), jejunal (J2), and ileal (IL16) HIEs were treated with 1% sow bile for the GII.4 variants or 5% human bile for GII.3 for 48 hours, and then inoculated with the indicated HuNoVs (GII.4/2006b-2, GII.4/2009, GII.4/2012-1: 9×105; GII.4/2006b-3: 5.5×105; GII.3: 4.3×105 genome equivalents) and cultured in the presence of bile. Genome equivalents were determined as indicated in Fig. 1. Error bars denote standard deviation.