Table 4. Aligned KRAS read distribution for HCT116 and HKE3.
| Replicate | 12wt / 13wt | 12wt / 13mut | 12mut / 13wt | Total |
|---|---|---|---|---|
| HCT116 a | 40 | 40 | 0 | 80 |
| HCT116 b | 36 | 34 | 0 | 70 |
| HCT116 c | 60 | 36 | 0 | 96 |
| HCT116 mean | 55.3% | 44.7% | 0.0% | |
| HKE3 a | 82 | 46 | 35 | 163 |
| HKE3 b | 55 | 46 | 30 | 131 |
| HKE3 c | 32 | 62 | 44 | 138 |
| HKE3 d | 31 | 48 | 38 | 117 |
| HKE3 mean | 36.4% | 36.8% | 26.8% |
The proportion of each read combination for each cell line is given in the last three columns. The approximate ratio of 1:1:0 (wt:G13D:G12C) for HCT116 is expected, but the ratio is closer to 1:1:1 for HKE3.