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Co-culture model. Merged DIC and fluorescent confocal images of a control (a) spheroid and one cultured with FITC-Dx-loaded nanogels for one hour (b). Confocal images of spheroids cultured in the presence of FITC-Dx-loaded nanogels without GRGDS (c) and with GRGDS (d) after two hours. The optical section shown in d was taken at 28 μm cell depth into the co-culture spheroid.
