Table 2. Non-invasive markers of subclinical atherosclerosis.
(A) Vascular inflammation by depression status. (B) Coronary plaque burden by depression status.
Parameter | Comorbid depression | No psychiatric history | p value |
---|---|---|---|
A | |||
Vascular inflammation by FDG-PET/CT | |||
Total aortic TBR | 1.82 ± 0.34 | 1.66 ± 0.18 | 0.008 |
Aortic arch TBR | 1.98 ± 0.36 | 1.84 ± 0.21 | 0.02 |
Descending aortic TBR | 1.81 ± 0.37 | 1.65 ± 0.18 | 0.01 |
Suprarenal aortic TBR | 1.90 ± 0.42 | 1.69 ± 0.24 | 0.007 |
Infrarenal aortic TBR | 1.79 ± 0.40 | 1.59 ± 0.19 | 0.003 |
B | |||
Plaque burden adjusted for luminal attenuation | |||
Total burden (×100), mm2 [median (IQR)] | 1.11 (0.85–1.49) | 0.98 (0.81–1.22) | 0.04 |
Non-calcified burden (×100), mm2 [median (IQR)] | 1.10 (0.83–1.45) | 0.93 (0.78–1.21) | 0.03 |
Dense calcified burden (×100), mm2 [median (IQR)] | 0.01 (0.005–0.03) | 0.01 (0.003–0.03) | 0.37 |
TBR = Target-to-Background Ratio.