. 2016 Apr 30;21(5):334–344. doi: 10.1007/s12199-016-0534-2

Table 4.

Spearman’s correlation test and multiple linear regression analyses of maternal TSH and FT4 by maternal PFOS and PFOA levels

	PFOS						PFOA
	Correlation^a		Crude^b		Adjusted^b,c		Correlation^a		Crude^b		Adjusted^b,c
	ρ	p value	β	p value	β	p value	ρ	p value	β	p value	β	p value
All mothers (n = 392)
TSH	−0.179	<0.001	−0.187	<0.001	−0.214	<0.001	0.042	0.412	0.056	0.272	0.039	0.478
FT4	0.083	0.100	0.069	0.176	0.061	0.236	0.023	0.651	0.023	0.646	0.004	0.946
Mothers of male infants (n = 180)
TSH	−0.194	0.009	−0.219	0.003	−0.246	0.002	−0.034	0.652	0.004	0.959	−0.067	0.435
FT4	0.118	0.114	0.113	0.130	0.093	0.208	0.058	0.437	0.023	0.755	0.023	0.762
Mothers of female infants (n = 212)
TSH	−0.164	0.017	−0.163	0.018	−0.210	0.005	0.108	0.119	0.101	0.142	0.114	0.124
FT4	0.056	0.422	0.032	0.648	0.030	0.684	−0.017	0.810	0.024	0.727	0.006	0.936

β with p < 0.05 are shown in bold

FT4 free thyroxine, PFOA perfluorooctanoate, PFOS perfluorooctane sulfonate, TSH thyroid stimulating hormone

^aSpearman’s correlation test

^bConcentrations of PFOS, PFOA, TSH, and FT4 are log 10 transformed

^cAdjusted for maternal age at delivery, BMI, parity, educational level, thyroid antibody, intake of seaweed, blood sampling period before/after delivery for PFOS and PFOA, and gestational week at which blood sampling was obtained for TSH and FT4