Table 4.
PFOS | PFOA | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Correlationa | Crudeb | Adjustedb,c | Correlationa | Crudeb | Adjustedb,c | |||||||
ρ | p value | β | p value | β | p value | ρ | p value | β | p value | β | p value | |
All mothers (n = 392) | ||||||||||||
TSH | −0.179 | <0.001 | −0.187 | <0.001 | −0.214 | <0.001 | 0.042 | 0.412 | 0.056 | 0.272 | 0.039 | 0.478 |
FT4 | 0.083 | 0.100 | 0.069 | 0.176 | 0.061 | 0.236 | 0.023 | 0.651 | 0.023 | 0.646 | 0.004 | 0.946 |
Mothers of male infants (n = 180) | ||||||||||||
TSH | −0.194 | 0.009 | −0.219 | 0.003 | −0.246 | 0.002 | −0.034 | 0.652 | 0.004 | 0.959 | −0.067 | 0.435 |
FT4 | 0.118 | 0.114 | 0.113 | 0.130 | 0.093 | 0.208 | 0.058 | 0.437 | 0.023 | 0.755 | 0.023 | 0.762 |
Mothers of female infants (n = 212) | ||||||||||||
TSH | −0.164 | 0.017 | −0.163 | 0.018 | −0.210 | 0.005 | 0.108 | 0.119 | 0.101 | 0.142 | 0.114 | 0.124 |
FT4 | 0.056 | 0.422 | 0.032 | 0.648 | 0.030 | 0.684 | −0.017 | 0.810 | 0.024 | 0.727 | 0.006 | 0.936 |
β with p < 0.05 are shown in bold
FT4 free thyroxine, PFOA perfluorooctanoate, PFOS perfluorooctane sulfonate, TSH thyroid stimulating hormone
aSpearman’s correlation test
bConcentrations of PFOS, PFOA, TSH, and FT4 are log 10 transformed
cAdjusted for maternal age at delivery, BMI, parity, educational level, thyroid antibody, intake of seaweed, blood sampling period before/after delivery for PFOS and PFOA, and gestational week at which blood sampling was obtained for TSH and FT4