Table 5.
PFOS | PFOA | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Correlationa | Crudeb | Adjustedb,c | Correlationa | Crudeb | Adjustedb,c | |||||||
ρ | p value | β | p value | β | p value | ρ | p value | β | p value | β | p value | |
All infants (n = 392) | ||||||||||||
TSH | 0.061 | 0.229 | 0.080 | 0.112 | 0.177 | 0.001 | −0.077 | 0.127 | −0.066 | 0.190 | −0.014 | 0.801 |
FT4 | 0.015 | 0.774 | 0.003 | 0.961 | −0.043 | 0.452 | −0.012 | 0.815 | 0.014 | 0.786 | 0.003 | 0.960 |
Male infants (n = 180) | ||||||||||||
TSH | 0.057 | 0.444 | 0.084 | 0.264 | 0.205 | 0.014 | −0.146 | 0.051 | −0.125 | 0.095 | −0.095 | 0.277 |
FT4 | 0.012 | 0.877 | −0.040 | 0.598 | −0.037 | 0.670 | −0.031 | 0.678 | 0.033 | 0.658 | 0.023 | 0.795 |
Female infants (n = 212) | ||||||||||||
TSH | 0.071 | 0.301 | 0.081 | 0.241 | 0.173 | 0.021 | −0.017 | 0.808 | −0.013 | 0.847 | 0.054 | 0.465 |
FT4 | 0.022 | 0.753 | 0.032 | 0.642 | −0.044 | 0.567 | 0.001 | 0.988 | −0.001 | 0.990 | −0.017 | 0.819 |
β with p < 0.05 are shown in bold
FT4 free thyroxine, PFOA perfluorooctanoate, PFOS perfluorooctane sulfonate, TSH thyroid stimulating hormone
aSpearman’s correlation test
bConcentrations of PFOS, PFOA, TSH, and FT4 are log 10 transformed
cAdjusted for maternal factors (maternal age at delivery, parity, thyroid antibody, blood sampling period before/after delivery for PFOS and PFOA, and values of TSH and FT4); and infant factors (gestational weeks at birth, low birth weight <2500 g, and mode of delivery)