. 2016 Apr 30;21(5):334–344. doi: 10.1007/s12199-016-0534-2

Table 5.

Spearman’s correlation test and multiple linear regression analyses of infant TSH and FT4 by maternal PFOS and PFOA levels

	PFOS						PFOA
	Correlation^a		Crude^b		Adjusted^b,c		Correlation^a		Crude^b		Adjusted^b,c
	ρ	p value	β	p value	β	p value	ρ	p value	β	p value	β	p value
All infants (n = 392)
TSH	0.061	0.229	0.080	0.112	0.177	0.001	−0.077	0.127	−0.066	0.190	−0.014	0.801
FT4	0.015	0.774	0.003	0.961	−0.043	0.452	−0.012	0.815	0.014	0.786	0.003	0.960
Male infants (n = 180)
TSH	0.057	0.444	0.084	0.264	0.205	0.014	−0.146	0.051	−0.125	0.095	−0.095	0.277
FT4	0.012	0.877	−0.040	0.598	−0.037	0.670	−0.031	0.678	0.033	0.658	0.023	0.795
Female infants (n = 212)
TSH	0.071	0.301	0.081	0.241	0.173	0.021	−0.017	0.808	−0.013	0.847	0.054	0.465
FT4	0.022	0.753	0.032	0.642	−0.044	0.567	0.001	0.988	−0.001	0.990	−0.017	0.819

β with p < 0.05 are shown in bold

FT4 free thyroxine, PFOA perfluorooctanoate, PFOS perfluorooctane sulfonate, TSH thyroid stimulating hormone

^aSpearman’s correlation test

^bConcentrations of PFOS, PFOA, TSH, and FT4 are log 10 transformed

^cAdjusted for maternal factors (maternal age at delivery, parity, thyroid antibody, blood sampling period before/after delivery for PFOS and PFOA, and values of TSH and FT4); and infant factors (gestational weeks at birth, low birth weight <2500 g, and mode of delivery)