Table 2.
Univariate and multivariate analysis of patient and tumor characteristics associated with pCR (ypT0/isN0) (n = 405)
| Characteristic | Univariate OR (95 % CI) | Univariate p value | Multivariate OR (95 % CI) | Multivariate p value |
|---|---|---|---|---|
| Age | 0.985 (0.959–1.012) | 0.276 | ||
| Menopausal status | 1.396 (0.739–2.638) | 0.304 | ||
| cT stage | 0.486 (0.226–1.045) | 0.065 | ||
| c Lymph nodes | 0.723 (0.381–1.369) | 0.319 | ||
| Grade | 6.353 (2.75–14.675) | 0.000 | 2.615 (1.009–6.777) | 0.048 |
| Histology | 0.334 (0.078–1.431) | 0.140 | ||
| ER | 0.891 (0.197–4.037) | 0.881 | ||
| PR | 0.171 (0.088–0.331) | 0.000 | 0.479 (0.216–1.063) | 0.070 |
| MammaPrint | 7.140 (1.694–30.101) | 0.007 | 1.922 (0.420–9.438) | 0.385 |
| BluePrint-subtype | 8.758 (4.440–17.273) | 0.000 | 3.301 (1.422–7.666) | 0.005 |
Significant values are given in bold at p ≤ 0.05
pCR pathological complete response, OR odds ratio, CI confidence interval, ER estrogen receptor, PR progesterone receptor