Table 4.
Median values and range of MMP-2 and the three MMP-9 forms gelatinolytic activities in sera from glioma, meningioma and intracranial metastasis patients
| MMP-9 (240 kDa) | MMP-9 (130 kDa) | MMP-9 (92 kDa) | MMP-2 (72 kDa) | |
|---|---|---|---|---|
| Healthy controls | 51.7 [27; 112.5] | 61.4 [48.8; 90.4] | 762.6 [248.7; 1274.8] | 438.9 [201.9; 1117.6] |
| High grade gliomas | 111.2 [47; 342.5]* | 98.8 [38.4; 213.8] | 1129.9 [470.2; 1684.2]* | 459.6 [69.8; 1025.7] |
| Low grade meningiomas | 91.5 [48.6; 232.9]* | 120.2 [51.6; 247.2] | 1038.9 [436.6; 1493.9]* | 490.3 [195.8; 1205.4] |
| High grade meningiomas | 113.7 [32.8; 222.6]* | 106 [45.6; 137.7] | 1185.9 [550.8; 1562.6]* | 617.8 [324.4; 794.4] |
| Intracranial metastasis | 154.7 [79.6; 403.1]* | 146.8 [45.2; 719.1] | 1224.9 [556.2; 2039.7]* | 501.9 [125.1; 1228.4] |
*Significantly different from controls (p < 0.01)