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. 2017 Feb 11;19(2):61. doi: 10.1007/s11051-017-3741-x

Graphical abstract.

Graphical abstract

We evaluate the extent of agreement between classification by electron microscopy (EM) and classification by Volume-Specific Surface Area (VSSA) on a large set of diverse particulate substances. These represent the challenges anticipated for identification of nanomaterials by the European Commission recommendation for a definition of nanomaterials for regulatory purposes.