Table 3.
Microsatellite instability in ATLL: reports in the literature
| Author | Year | No. of cases | Subject | Locus | No. of loci | Detection | MSI | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Tumour | Control | %MSI | %H | %L | ||||||
| Hatta et al. | 1998 | 22 | Unknown | PB | di- | 54 | R | 45 | 0 | 45 |
| Hayami et al. | 1999 | 18 | PB or LN | Hair root | mono-/di-/tri-/tetra- | 6 | R | 44 | 22 | 22 |
| Ohshima et al. | 2000 | 10 | Unknown | Placenta | TGFBR2, IGF2R, BAX | 3 | F | 0 | 0 | 0 |
| Komatsu et al. | 2000 | 10 (all MSI +) |
Unknown | – | TGFBR2, IGF2R, BAX, E2F4, MSH3 | 5 | Seq | – | – | – |
| Takeuchi et al. | 2003 | 11 | Cell line | – | mono- | 1 | R | 18 | 18 | NE |
di- dinucleotide microsatellites, F fluorescence, LN lymph nodes, mono- mononucleotide microsatellites, MSI microsatellite instability, NE not evaluated, PB peripheral blood, R autoradiography, Seq sequencing, tetra- tetranucleotide microsatellites, tri- trinucleotide microsatellites, %H MSI-H (high), %L MSI-L (low)