Table 1.

Sequence analysis of the CAN1 gene from canavanine resistant Kllsm4Δ1 and CML39-11A clones obtained from 1 day cultures

Strain	Clone	Mutation type			Position from ATG	Sequence
Kllsm4Δ1	1	Base substitution	G → T	Vali-Phe	703	CATCAAAGTTTT
		Insertion	G		708	TTTTA-G-GCCATTA
	2	Base substitution	G → A	Glu-Lys	424	TTGGGTGAAATG
	3	Base substitution	C → T	Glu-STOP	568	AGTTGGCCAAGT
	4	Base substitution	G → T	Glu-STOP	679	TGAATTCGAGTT
	5	No change
	6	No change
	7	No change
	8	No change
	9	No change
	10	No change
CML39-11A	1	Insertion	T		496	CATTTTGGTGCG
	2	Base substitution	G → T	Gly-Cys	352	AACGCCGGCCCA
	3	Base substitution	G → T	Glu-STOP	226	TGAAGATGAAGG
	4	Base substitution	G → T	Glu-STOP	226	TGAAGATGAAGG
	5	Base substitution	A → C	Leu-Phe	330	TGGTTTATCCAC
	6	Base substitution	C → G	Ser-STOP	11	CAAATTCAAAAG
	7	No change
	8	Partially sequenced
	9	Partially sequenced