Table 2.
Multiple ordered logistic regression analysis with Ishak fibrosis stages as the dependent variable in patients with chronic hepatitis B
| Variable | Fib-model | Cirrh-model | ||||
|---|---|---|---|---|---|---|
| β | OR (95 % CI) | P | β | OR (95 % CI) | P | |
| C5a | −0.013 | 0.987 (0.976, 0.999) | 0.029 | −0.045 | 0.956 (0.932, 0.980) | <0.001 |
| logCO-IV | 1.832 | 6.249 (0.749, 52.159) | 0.091 | 3.686 | 39.900 (2.320, 686.252) | 0.011 |
| logHBsAg | −0.948 | 0.388 (0.243, 0.617) | <0.001 | −0.582 | 0.559 (0.286, 1.091) | 0.088 |
| Albumin | −0.046 | 0.955 (0.884, 1.031) | 0.234 | −0.198 | 0.820 (0.734, 0.917) | <0.001 |
| Platelet count | −0.017 | 0.984 (0.976, 0.991) | <0.001 | −0.016 | 0.984 (0.975, 0.994) | 0.002 |
| AST | 0.006 | 1.006 (0.999, 1.013) | 0.090 | 0.003 | 1.003 (0.994, 1.013) | 0.463 |
| LN | 0.004 | 1.004 (1.001, 1.007) | 0.012 | 0.001 | 1.001 (0.997, 1.004) | 0.699 |
OR odds ratio, CI confidence interval, C5a complement 5a, CO-IV collagen IV, HBsAg HBV surface antigen, AST aspartate transaminase, LN laminin