Table 1.
Genome-wide association studies in suicidal behavior and ideation.
| Clinical finding | Sample size (cases) | Total No. of SNPs | SNP (Gene) | References |
|---|---|---|---|---|
| Suicidal ideation | 180 (90) | 109,365 | rs11628713 (PAPLN), rs10903034 (IL28RA) | Laje et al., 2009 |
| Suicidal ideation | 706 (244) | 539,199 | rs11143230 (GDA), rs4732812 (ELP3) rs358592 (KCNIP4) | Perroud et al., 2012 |
| Suicidal ideation | 397 (32) | 371,335 | rs1037448 (TMEM138) rs10997044 (CTNNA3) rs1109089 (RHEB) | Menke et al., 2012 |
| Suicide attempters | 3,117 (1,295) | ~1.9 × 106 | rs2576377 (ABI3BP) rs4918918 (SORBS1) rs10854398 (B3GALT5) rs1360550 (PRKCE) | Perlis et al., 2010 |
| Suicide attempters | 2,023 (251) | 532,774 | rs4751955 (GFRA1), rs203136 (KIAA1244) | Schosser et al., 2011 |
| Suicide attempters | 5,815 (2,496) | ~730,000 | rs300774 (2p25, ACP1, SH3YL1, FAM150B) | Willour et al., 2012 |
| Suicide completers | 99 (68) | 37,344 | 58 SNPs (19 genes) | Galfalvy et al., 2013 |
| Suicide attempters | 3,270 (426) | 532,774 | rs17173608 (RARRES2) rs17387100 (PROM1) rs3781878 (NCAM1) | Mullins et al., 2014 |
| Suicide attempters and suicide completers | 1,800 (577) | 794,207 | rs11852984 (intergenic) rs6480463 (ADAMTS14) rs4575 (PSME2/RNF31) rs336284 (TBX20) rs3019286 (STK3) | Galfalvy et al., 2015 |
SNP, single-nucleotide polymorphism.