Table 2.
Obstetric and perinatal outcomes
| MACS group (N = 49) | Control group (N = 51) | P | |
|---|---|---|---|
| Pregnancy outcome | |||
| 1st trimester bleeding | 28.6 (15.9–41.2) | 23.5 (11.9–35.1) | NS |
| Invasive proceduresa | 2.0 (0–5.9) | 3.9 (0–9.2) | NS |
| Anemia (Hb <11 g/dl) | 6.1 (0–12.8) | 5.9 (0–12.4) | NS |
| Gestational cholestasis | 0 (0–0) | 3.9 (0–9.2) | NS |
| Diabetes | 14.3 (4.5–24.1) | 9.8 (1.6–17.9) | NS |
| 2nd and 3rd trimester bleeding | 10.2 (1.7–18.7) | 5.9 (0–12.4) | NS |
| PROM <37 weeks | 6.1 (0–12.8) | 5.9 (0–9.2) | NS |
| Pregnancy-induced hypertension | 6.1 (0–12.8) | 15.7 (5.7–25.7) | NS |
| Urinary tract infection | 8.2 (0.5–15.9) | 3.9 (0–9.2) | NS |
| Delivery outcome | |||
| Weeks at delivery | 36.6 (35.1–38.1) | 36.4 (35.1–38.8) | NS |
| Preterm births (<37 weeks) | 28.6 (15.9–41.2) | 31.3 (18.6–44.0) | NS |
| Very preterm births (<34 weeks) | 12.2 (3.0–21.4) | 10.2 (1.9–18.5) | NS |
| Cesarean section | 71.4 (58.7–84.0) | 66.7 (53.8–79.6) | NS |
| Neonatal outcome | |||
| (N = 65) | (N = 66) | ||
| Female neonates | 40.0 (26.3–53.7) | 54.5 (40.8–68.2) | NS |
| Birth weight (g) | 2684.1 (2499.5–2868.7) | 2676.1 (2499.0–2852.2) | NS |
| Birth weight female neonate (g) | 2627 (2345–2908) | 2564 (2325–2803) | NS |
| Birth weight male neonate (g) | 2722 (2465–2978) | 2841 (2572–3109) | NS |
| LBW (<2500 g) | 40.4 (26.6–54.1) | 38.0 (24.7–51.3) | NS |
| VLBW (<1500 g) | 6.1 (0–9.5) | 4.5 (0–10.2) | NS |
| Neonatal height (cm) | 48.3 (47.1–49.4) | 46.5 (44.6–48.4) | NS |
| Apgar score at 1 min | 8.8 (8.3–9.3) | 8.9 (8.6–9.2) | NS |
| Apgar score at 5 min | 9.7 (9.5–9.9) | 9.5 (9.2–9.7) | NS |
| Apgar score at 10 min | 9.8 (9.4–10.0) | 9.8 (9.5–10.0) | NS |
| Birth defects | 4.1 (0–9.6) | 2 (0–5.8) | NS |
| Major malformations | 0 (0–0) | 0 (0–0) | NS |
| Minor malformations | 4.1 (0–9.6) | 2 (0–5.8) | NS |
| Admission to NICU | 13.8 (4.1–23.5) | 12.1 (3.1–21.0) | NS |
| Days at the NICU | 15 (1–30) | 16 (10–23) | NS |
Values expressed as N (%) or mean (95% confidence interval)
LBW low birth weight, VLBW very low birth weight, SGA small for gestational age, NS not significant, Hb hemoglobin, PROM premature rupture of membranes
aChorionic villus sampling or amniocentesis: no abnormal results found