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. 2016 Dec 2;31(2):241–257. doi: 10.1038/eye.2016.275

Table 2. Risk factors for the growth of iris nevus into melanoma.

Initial Feature Hazard ratio % of patients with tumor growth having this feature % of patients with no tumor growth having this feature
A Age ≤40 years 3 48 24
B Blood 9 11 <1
C Clock hour-inferior 9 96 71
D Diffuse configuration 14 4 <1
E Ectropion uveae 4 48 18
F Feathery margin 3 52 24

Adapted from Shields et al.30