Figure 5.

Sensitivity and specificity of autoantibody patterns for diagnosis. Receiver operating characteristic for comparison of autoantibody reactivities in serum samples of primary open-angle glaucoma patients (POAG; N=20) and non-glaucomatous controls (N=13) using specific antigen microarrays in combination with an artificial neural network (X-axis: 1-specificity, Y axis: sensitivity, R=0.93). The sensitivity and specificity for a discrimination of prospective glaucoma and control subjects was 93%. (Reprinted from Boehm et al,⁵⁰ with permission from Elsevier).