Skip to main content
. 2017 Jan 31;2017:5196958. doi: 10.1155/2017/5196958

Figure 2.

Figure 2

The enhancement of BPA on hippocampal LTP was ER-dependent. (a) Administration of ICI 182,780 10 nM (an antagonist of ERs, filled square, n = 8) remarkably decreased the 100 nM BPA-induced enhancement of LTP. Pretreatment with the ERs antagonist ICI 182,780 30 min before BPA 100 nM (open squares, n = 8) application completely blocked BPA-enhanced LTP compared with BPA alone. (b) Figure columns express the average fEPSP amplitudes after HFS in separate perfusion or coperfusion of BPA 100 nM and ICI 182,780 100 nM, ∗∗∗p < 0.001 as compared to the control, ###p < 0.001 as compared to the BPA 100 nM. Solid and dashed example traces before HFS and after HFS, respectively.