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. 2017 Jan 31;2017:5196958. doi: 10.1155/2017/5196958

Figure 4.

Figure 4

The enhancement of BPA on hippocampal LTP was abolished by E2 treatment. Enhanced LTP by E2 (10 nM) in hippocampal area DG (open triangles, n = 8). Coadministration of BPA 100 nM with E2 (filled triangles, n = 8) had no effect on LTP compared with untreated controls. (b) Pretreatment by E2 enhanced the pre-HFS EPSP amplitudes, ∗∗∗p < 0.001 as compared to controls, ###p < 0.001 as compared to the E2 10 nM. (c) Comparison of different groups the fEPSP amplitudes at 60 min. E2 had no effect on LTP compared with untreated controls without baseline increase in EPSP amplitude (before the HFS). ∗∗∗p < 0.001 as compared to the control, ##p < 0.01 as compared to the BPA 100 nM. Solid and dashed traces are examples of before treatment, after treatment, and after HFS, respectively.