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E6/E7 inhibitory siRNAs do not induce senescence in hypoxic HPV-positive cancer cells. HeLa cells were transfected with E6/E7 inhibitory siRNAs (si18E6/E7) or control siRNA (siContr-1) and cultivated under normoxia (21% O2) or hypoxia (1% O2). After 72 h, cells were stained for expression of the senescence marker SA-β-Gal. (Scale bar: 200 µm.)
