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. 2017 Feb 13;17:51. doi: 10.1186/s12862-017-0893-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Radical changes of sites under selection are shown in crystal structure of a: Hba, b: Hbb, and c: Mb with red. The site in Mb identified along lineages leading to Brachyhypopomus gauderio and Electrophorus electricus is marked with pink (residue 109). Cys substitutions of Electrophorus electricus at Mb gene are marked with green (residue 106 and 108)