Table 6.

Controllability and observability index values for the model of ERK activation controlled via the EGFR pathway

Lumped	Controllability	Observability	Input-output
state-variable	index	index	index
x 1(t)	0.3022	0.0176	0.0053
x 2(t)	0.0201	0.0153	0.0003
x 3(t)	0.0189	0.0009	1.681×10−5
x 4(t)	0.8547	0.2752	0.2352
x 5(t)	0.6194	0.0079	0.0049
x 6(t)	1	1	1
x 7(t)	0.1412	0.1043	0.0147
x 8(t)	0.1378	0.0018	0.0003
x 9(t)	0.1539	0.0164	0.0025
x 10(t)	0.0473	0.0092	0.0004
x 11(t)	0.3312	0.0442	0.0146