Table 1.

Cardiovascular Disease and Mortality Outcomes Ascertainment in WHI

Study Outcome	Definition and Confirmation of Outcomes
Non-fatal myocardial infarction	Standardized criteria for diagnostic electrocardiography changes, elevated cardiac enzymes or both
Revascularization	Documentation of the procedure in the medical record.
Angina	Hospital record, angiography evidence, diagnostic stress test, or documented physician diagnosis and medical treatment
Congestive heart failure	Hospital record and diagnostic confirmatory tests
Fatal coronary heart disease	Documentation in the hospital record, autopsy report or cause of death on the death certificate with evidence of previous coronary heart disease
Stroke	Documentation in the medical record of neurologic deficit of rapid onset consistent with stroke and lasting for at least 24 h or until death
Death from other cardiovascular disease	Confirmatory evidence in the medical records as ascertained by physician adjudicators