Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 13;16:28. doi: 10.1186/s12934-017-0638-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 1 — Sequence homology of α-galactosidases from different sources. The amino acid sequences of Thermus thermophilus HB27 (Accession No. AAS82402), Thermus sp. strain T2 (75%), Thermus brockianus (73%), Thermotoga neapolitana (36%), Thermotoga maritima (35%), Sulfolobus solfataricus (39%) and Homo sapiens (23%) were aligned for optimal sequence similarity using the program CLUSTAL W. a The consensus motif ([LIVMFY]-x(2)-[LIVMFY]-x-[LIVM]-D-D-x-[WY]) is characteristic of α-galactosidases; b amino acid stretches including two conserved cysteine residues; c amino acid stretches surrounding the aspartic acids responsible for the nucleophilic and acid–base catalytic mechanism. Conserved amino acids are highlighted with asterisk in T. thermophilus HB27 sequence