Fig. 5.

Lung inflammation in lung after 3 weeks intranasal instillation of SPD-MAA. Both WT and SR-A1 KO mice were treated intranasally with saline, SPD-MAA (50 μg/mL) and SPD (50 μg/mL) for 3 weeks. A representative 4–5 μm thick section of H and E stained of one mouse per treatment group is shown (10 × magnification). WT Saline a, SPD-MAA b, SPD c and SR-A1 KO Saline d, SPD-MAA (E), SPD f. Line scale represents approx. 100 μm. Arrow denotes the localization of inflammatory cells