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. 2017 Feb 13;12:30. doi: 10.1186/s13023-017-0585-5

Fig. 1.

Fig. 1

a. Propionic acid effects on IKs current in KCNQ1/KCNE1-CHO cells. Representative whole cell current traces at baseline, after the application of PA (5 mM, blue), and after brief wash-out (grey), demonstrating an acute reduction of IKs by 50%. Voltage clamp protocol is shown in the inset. b. Propionic acid effects on action potential in human iPSC-CMs. Superimposed representative AP traces at baseline and after PA (5 mM, blue), indicating an AP-prolongation