Table 5.
Odds of use of Anxiolytics or Sedatives or at one time point given use of Anxiolytics or Sedatives at a previous time point, covariates measured at the “previous” time point, N = 1406 observations
| Variables | Anxiolytics | Sedatives | ||||||
|---|---|---|---|---|---|---|---|---|
| Unadjusted | Adjusted | Unadjusted | Adjusted | |||||
| OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Assessed at previous time point | ||||||||
| CDR sum of boxes | 0.96 (0.94; 0.99) | 0.015 | 0.97 (0.94; 1.01)4 | 0.125 | 0.94 (0.91; 0.97) | <0.001 | 0.94 (0.91; 0.97)1 | <0.001 |
| GMHR | ||||||||
| Good | 1.31 (0.68; 2.54) | 0.421 | 1.20 (0.65; 2.23) | |||||
| Fairly good | 1.56 (0.87; 2.81) | 0.138 | 1.42 (0.82; 2.47) | 0.560 | ||||
| Poor | 1.83 (1.01; 3.30) | 0.046 | 1.43 (0.82; 2.49) | 0.209 | ||||
| Very Poor | 1 | - | 1 | 0.212 | ||||
| PSMS score | 0.96 (0.93; 0.98) | 0.002 | 0.96 (0.93; 0.99)3 | 0.016 | 0.95 (0.93; 0.98) | - | ||
| NPI Agitation sub-syndrome | 1.00 (0.98; 1.02) | 0.964 | 0.99 (0.97; 1.01) | 0.001 | ||||
| NPI Psychosis sub-syndrome | 1.01 (0.98; 1.04) | 0.451 | 1.00 (0.97; 1.04) | 0.358 | ||||
| NPI Affective sub-syndrome | 1.08 (1.05; 1.11) | <0.001 | 1.09 (1.06; 1.12)1 | <0.001 | 1.04 (1.01; 1.07) | 0.878 0.005 |
1.06 (1.03; 1.09)2 | <0.001 |
| NPI Apathy | 1.01 (0.97; 1.05) | 0.662 | 0.94 (0.90; 0.99) | 0.012 | 0.95 (0.90; 0.996)4 | 0.034 | ||
| Assessed at baseline | ||||||||
| Age | 0.997 (0.98; 1.02) | 0.775 | 1.002 (0.98; 1.02) | 0.812 | ||||
| Females | 1.01 (0.71; 1.44) | 0.967 | 1.28 (0.89; 1.83) | 0.182 | ||||
| Education (<=10 years) | 1.16 (0.81; 1.66) | 0.416 | 0.82 (0.59; 1.15) | 0.253 | 0.77 (0.54; 1.08)5 | 0.125 | ||
| Duration in NH (LN) | 1.07 (0.94; 1.22) | 0.292 | 1.12 (0.98; 1.28)5 | 0.101 | 0.91 (0.81; 1.04) | 0.164 | ||
| Nursing home size | 1.01 (1.002; 1.01) | 0.004 | 1.007 (1.002; 1.011)2 | 0.002 | 1.00 (0.999; 1.01) | 0.109 | 1.004 (1.00; 1.008)3 | 0.072 |
| Type of nursing home unit | ||||||||
| RU | 1 | - | 1 | - | ||||
| REU | 0.18 (0.02; 1.83) | 0.146 | 2.35 (0.63; 8.79) | 0.206 | ||||
| 0.754 | 0.62 (0.39; 0.98) | 0.041 | ||||||
| SCU | 0.93 (0.58; 1.49) | |||||||
| OU | 2.96 (0.54; 16.13) | 0.209 | 1.67 (0.34; 8.19) | 0.526 | ||||
RU Regular units
REU rehabilitation unit
SCU special care unit for people with dementia
OU other units
The relative importance of each covariate in the adjusted models is included with a number after the 95% CI; lowest number has highest importance