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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: J Trauma Acute Care Surg. 2016 Aug;81(2):358–365. doi: 10.1097/TA.0000000000001056

Figure 2. Intraluminal tranexamic acid reduces pulmonary injury and inflammation following hemorrhagic shock.

Figure 2

C57BL/6J mice underwent 90 minutes of hemorrhagic shock followed by the intraluminal injection of tranexamic acid into the small intestine. Three hours later, lungs were analyzed for histopathologic injury using a three point scoring system; representative photomicrographs are shown. Myeloperoxidase immunofluorescence staining was used to assess lung inflammation; representative images shown along with the corresponding images. Results are expressed as mean SE; n=8/group. Abbreviations: HS= hemorrhagic shock; TXA- tranexamic acid; MPO=myeloperoxidase; RFU= relative fluorescent units