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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: J Allergy Clin Immunol. 2017 Feb;139(2):415–421. doi: 10.1016/j.jaci.2016.12.002

Figure 2. Vertical and induced epigenetic transmission models.

Figure 2

Vertical epigenetic transmission model proposes direct transfer of epigenetic information from parents to child in successive generations (A). The alternative model, induced epigenetic transmission, proposes that maternal disease is an essential element in the chain of epigenetic transmission of information (B). DNA-M: DNA methylation