Table 5.
Discriminative accuracy and comparison of the discriminative accuracy of the different frailty, comorbidity, or disability instruments (full scales) for 1-year mortality
| AUC (95% CI) | P-value |
P-value, AUC 1 vs AUCs 2, 3, 4, 5, 6, and 7 |
P-value, AUC 2 vs AUCs 1, 3, 4, 5, 6, and 7 |
P-value, AUC 3 vs AUCs 1, 2, 4, 5, 6, and 7 |
P-value, AUC 4 vs AUCs 1, 2, 3, 5, 6, and 7 |
P-value, AUC 5 vs AUCs 1, 2, 3, 4, 6, and 7 |
P-value, AUC 6 vs AUCs 1, 2, 3, 4, 5, and 7 |
P-value, AUC 7 vs AUCs 1, 2, 3, 4, 5, and 6 |
|
|---|---|---|---|---|---|---|---|---|---|
| All patients (n=305) | |||||||||
| 1. CFS-7 | 0.841 (0.788–0.893) | <0.001 | – | 0.047 | <0.001 | 0.004 | <0.001 | <0.001 | ,0.001 |
| 2. FI | 0.812 (0.754–0.869) | <0.001 | 0.047 | – | <0.001 | 0.045 | <0.001 | <0.001 | ,0.001 |
| 3. FRAIL scale | 0.727 (0.661–0.792) | <0.001 | <0.001 | <0.001 | – | 0.096 | 0.489 | 0.296 | 0.154 |
| 4. CIRS-G | 0.770 (0.708–0.913) | <0.001 | 0.004 | 0.045 | 0.096 | – | 0.041 | 0.225 | 0.339 |
| 5. Comorbidity-D-FI | 0.726 (0.663–0.789) | <0.001 | <0.001 | <0.001 | 0.489 | 0.041 | – | 0.329 | 0.208 |
| 6. ADL-Katz | 0.744 (0.674–0.814) | <0.001 | <0.001 | <0.001 | 0.296 | 0.225 | 0.329 | – | 0.232 |
| 7. IADL/ADL-D-FI | 0.757 (0.695–0.819) | <0.001 | <0.001 | <0.001 | 0.154 | 0.339 | 0.208 | 0.232 | – |
| Subgroup of patients aged 65–82 years (n=139) | |||||||||
| 1. CFS-7 | 0.844 (0.767–0.922) | <0.001 | – | 0.003 | 0.003 | 0.018 | 0.006 | <0.001 | ,0.001 |
| 2. FI | 0.752 (0.639–0.865) | <0.001 | 0.003 | – | 0.281 | 0.456 | 0.299 | 0.011 | 0.044 |
| 3. FRAIL scale | 0.727 (0.619–0.835) | 0.002 | 0.003 | 0.281 | – | 0.285 | 0.479 | 0.243 | 0.313 |
| 4. CIRS-G | 0.757 (0.650–0.864) | <0.001 | 0.018 | 0.456 | 0.285 | – | 0.217 | 0.088 | 0.162 |
| 5. Comorbidity-D-FI | 0.724 (0.618–0.830) | 0.002 | 0.006 | 0.299 | 0.479 | 0.217 | – | 0.231 | 0.378 |
| 6. ADL-Katz | 0.668 (0.525–0.812) | 0.019 | <0.001 | 0.011 | 0.243 | 0.088 | 0.231 | – | 0.104 |
| 7. IADL/ADL-D-FI | 0.703 (0.588–0.818) | 0.004 | <0.001 | 0.044 | 0.313 | 0.162 | 0.378 | 0.104 | – |
| Subgroup of patients aged ≥83 years (n=166) | |||||||||
| 1. CFS-7 | 0.834 (0.763–0.904) | <0.001 | – | 0.394 | <0.001 | 0.036 | 0.006 | 0.014 | 0.039 |
| 2. FI | 0.840 (0.774–0.907) | <0.001 | 0.394 | – | <0.001 | 0.016 | 0.001 | 0.001 | 0.002 |
| 3. FRAIL scale | 0.724 (0.640–0.807) | <0.001 | <0.001 | <0.001 | – | 0.165 | 0.492 | 0.127 | 0.063 |
| 4. CIRS-G | 0.768 (0.689–0.846) | <0.001 | 0.036 | 0.016 | 0.165 | – | 0.099 | 0.494 | 0.339 |
| 5. Comorbidity-D-FI | 0.725 (0.645–0.806) | <0.001 | 0.006 | 0.001 | 0.492 | 0.099 | – | 0.465 | 0.109 |
| 6. ADL-Katz | 0.770 (0.691–0.850) | <0.001 | 0.014 | 0.001 | 0.127 | 0.494 | 0.465 | – | 0.246 |
| 7. IADL/ADL-D-FI | 0.785 (0.711–0.859) | <0.001 | 0.039 | 0.002 | 0.063 | 0.339 | 0.109 | 0.246 | – |
Abbreviations: ADL, basic activities of daily living; ADL-Katz, disability burden based on the six ADLs of the Katz index; AUC, area under the curve; CFS-7, Canadian Study on Health and Aging Clinical Frailty Scale; FI, frailty index; CIRS-G, Cumulative Illness Rating Scale for Geriatrics; Comorbidity-D-FI, Comorbidity domain of the frailty index; IADL, instrumental activities of daily living; IADL/ADL-D-FI, IADL/ADL domain of the frailty index.