Table 1.
Demographic data of participants
| Characteristics | Sequence AB | Sequence BA | |
|---|---|---|---|
| Age (years) | Median [range] | 47.4 [28–61] | 46.8 [26–64] |
| 25–45 years n (%) | 16 (47.1) | 18 (51.4) | |
| >45 years n (%) | 18 (52.9) | 17 (48.6) | |
| Marital status: n (%) | Single | 2 (6) | 0 |
| Married | 32 (94) | 35 (100) | |
| Education level: n (%) | Illiterate | 11 (32) | 12 (34) |
| Elementary | 15 (44) | 15 (43) | |
| Diploma | 7 (21) | 7 (20) | |
| Higher | 1 (3) | 1 (3) | |
| Employment: n (%) | Housewife | 27 (79) | 31 (89) |
| Employed | 7 (21) | 11 (4) | |
| Family history of malignancy: n (%) | Yes | 3 (9) | 3 (9) |
| No | 31 (91) | 32 (91) | |
| Pathology of cancer: n (%) | Inductal | 30 (88) | 29 (83) |
| Lobular | 3 (9) | 5 (14) | |
| Mixed inductal and lobular | 1 (3) | 1 (3) | |
| Cancer grade: n (%) | I | 0 | 0 |
| II | 28 (82) | 32 (91) | |
| III | 6 (18) | 3 (9) | |
| IV | 0 | 0 | |
| History of pregnancy vomiting: n (%) | Yes | 10 (29) | 10 (28) |
| No | 24 (71) | 25 (72) | |
| Alcohol use: n (%) | Yes | 2 (5.9) | 0 |
| No | 32 (94.1) | 35 (100) | |
| Smoking: n (%) | Yes | 3 (8.8) | 4 (11.4) |
| No | 31 (91.2) | 31 (88.6) | |
Sequence AB: Intervention by Persumac before crossover and then Placebo after crossover; Sequence BA: Intervention by Placebo before crossover and then Persumac after crossover.