Table 7.
Second Order Rate Constants for GSH Addition to α,β-Unsaturated Carbonyls
| ||||||||
|---|---|---|---|---|---|---|---|---|
| Aldehyde | Ketones | Esters | ||||||
| Entry | Structure | kGSH (M−1s−1) | Entry | Structure | kGSH (M−1s−1) | Entry | Structure | kGSH (M−1s−1) |
| 1 |
|
487 | 10 |
|
1173 | 19 |
|
105 |
| 2 |
|
203 | 11 |
|
80.0 | 20 |
|
51.4 |
| 3 |
|
59.4 | 12 |
|
26.7 | 21 |
|
19.6 |
| 4 |
|
28.3 | 13 |
|
25.6 | 22 |
|
10.6 |
| 5 |
|
22.8 | 14 |
|
11.4 | 23 |
|
8.54 |
| 6 |
|
18.0 | 15 |
|
0.779 | 24 |
|
0.785 |
| 7 |
|
3.49 | 16 |
|
0.208 | 25 |
|
0.164 |
| 8 |
|
1.71 | 17 |
|
0.200 | 26 |
|
0.072 |
| 9 |
|
0.474 | 18 |
|
0.074 | 27 |
|
0.007 |