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. 2017 Feb 7;10:657–665. doi: 10.2147/OTT.S125418

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© 2017 Ning et al. This work is published and licensed by Dove Medical Press Limited

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Subcellular localizations and expression patterns of Kindlin proteins in human osteosarcoma tissues.

Notes: The positive Kindlin-1 (A) Kindlin-2 (C) and Kindlin-3 (E) protein immunostainings were localized in the cytoplasm, nucleus and cytoplasm, respectively, of tumor cells in primary osteosarcoma tissues. Statistically, the expression levels of Kindlin-1 (B) and Kindlin-2 (D) proteins in osteosarcoma tissues were both significantly higher, but that of Kindlin-3 protein (F) was dramatically lower than those in noncancerous bone tissues. The subcellular localizations and expression patterns of Kindlins were examined by immunohistochemistry.