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. 2017 Feb 8;10:703–709. doi: 10.2147/OTT.S129042

Table 2.

Stratification analysis for associations of HACE1 gene polymorphisms with neuroblastoma susceptibility

Variables	rs4336470 (cases/controls)		Adjusted OR (95% CI)	P-value^a	rs9404576 (cases/controls)		Adjusted OR (95% CI)	P-value^a	Risk genotype (cases/controls)		Adjusted OR (95% CI)	P-value^a
Variables	CC	CT/TT	Adjusted OR (95% CI)	P-value^a	TT	TG/GG	Adjusted OR (95% CI)	P-value^a	0–3	4–5	Adjusted OR (95% CI)	P-value^a
Age, months
≤18	54/131	44/101	1.06 (0.66–1.71)	0.809	54/131	44/101	1.06 (0.66–1.71)	0.806	69/178	29/54	1.39 (0.82–2.37)	0.223
>18	76/172	75/126	1.33 (0.90–1.98)	0.154	80/172	71/126	1.20 (0.81–1.78)	0.374	98/212	53/86	1.32 (0.87–2.01)	0.192
Gender
Female	52/140	49/92	1.45 (0.90–2.33)	0.124	53/140	48/92	1.40 (0.87–2.24)	0.169	70/173	31/59	1.30 (0.78–2.18)	0.315
Male	78/163	70/135	1.08 (0.73–1.60)	0.702	81/163	67/135	1.00 (0.67–1.48)	0.982	97/217	51/81	1.40 (0.92–2.14)	0.121
Sites of origin
Adrenal gland	24/303	22/227	1.23 (0.67–2.26)	0.506	23/303	23/227	1.35 (0.73–2.47)	0.337	31/390	15/140	1.34 (0.70–2.57)	0.375
Retroperitoneal	40/303	41/227	1.36 (0.85–2.18)	0.196	41/303	40/227	1.30 (0.81–2.08)	0.275	52/390	29/140	1.55 (0.94–2.54)	0.083
Mediastinum	47/303	43/227	1.23 (0.79–1.93)	0.362	50/303	40/227	1.08 (0.69–1.69)	0.746	61/390	29/140	1.33 (0.82–2.16)	0.242
Others	14/303	10/227	0.93 (0.40–2.13)	0.855	15/303	9/227	0.78 (0.33–1.81)	0.558	18/390	6/140	0.94 (0.37–2.43)	0.904
Clinical stages
I + II +4s	60/303	58/227	1.29 (0.87–1.93)	0.211	63/303	55/227	1.16 (0.78–1.74)	0.458	79/390	39/140	1.39 (0.90–2.14)	0.135
III + IV	61/303	57/227	1.31 (0.87–1.96)	0.197	62/303	56/227	1.26 (0.84–1.90)	0.259	77/390	41/140	1.51 (0.98–2.31)	0.060

Note:

^a

Adjusted for age and gender.

Abbreviations: CI, confidence interval; OR, odds ratio.