Figure 4.

The microscopic hematoxylin-and-eosin histology slides of kidney for toxicity assessment of selected mice.

Notes: Mice were treated with 3.125 μg kg⁻¹ bw of GW in TA (A), TB (B), TC (C), TD (D), CN (E) and CI (F) groups. TA stands for acute exposure without infection, TB stands for acute exposure immediately within 2 hours after infection, TC represents subacute exposure without infection and TD stands for subacute exposure immediately within 2 hours after infection; CN, normal control mice without any infection and treatment; CI, single-dose infected normal mice. No signs of toxic effects in the kidney were observed for all groups of mice treated with 3.125 μg kg⁻¹ bw of GW. The kidney showed normal cellular structure with intact glomeruli and tubules. There was also no sign of necrosis or cellular damage. Microscopic images were viewed at 100× magnification.

Abbreviations: bw, body weight; GW, gancidin W.