Table 4.

ALT, AST and ALP levels (IU L⁻¹), as well as the STP level (g dL⁻¹), in the mice treated with gancidin W (GW) at 3.125 μg kg⁻¹ bw under four toxicity regimens

Regime	ALT (IU L−1)	AST (IU L−1)	ALP (IU L−1)	STP (g dL−1)
Acute exposure
TA	41.81±2.14*	133.13±2.04*	62.76±2.33*	6.12±2.32*
TB	45.20±1.13*	125.93±2.12*	59.42±2.97*	7.21±3.81*
Subacute exposure
TC	67.57±2.91*	167.76±2.27*	69.29±2.90*	7.93±2.01*
TD	95.03±2.02*,a	212.01±2.33*,b	68.03±2.10*	8.83±3.90*
Control exposure
CN	41.03±3.91*	111.62±1.19*	61.46±2.46*	6.40±1.01*
CI	44.83±1.11*	134.43±4.01*	58.32±2.97*	6.80±3.06*
Indicator
NR‡	40–93	92–206	54–115	5.8–9.5

Notes:

^*Value in mean ± standard deviation.

^aALT level recorded for the mice in the TD group, which was slightly higher than the NR.

^bAST level recorded for the mice in the TD group, which was slightly higher than the NR.

^‡NR indicates the normal range data for ICR strain male mice aged >8 weeks old for the indicator, as supplied by Research Animal Resources, University of Minnesota, MN, USA; the data present the values under the four toxicity regimens – TA, TB, TC and TD – as compared with the control regimens CN and CI. TA, stands for acute exposure to gancidin W without infection; TB, acute exposure immediately within 2 hours after infection; TC, subacute exposure without infection; TD, subacute exposure immediately within 2 hours after infection. CN, normal control mice without any infection and treatment; CI, single-dose infected normal mice.

Abbreviations: ALT, alanine aminotransferase; ALP, alkaline phosphatase; AST, aspartate aminotransferase; bw, body weight; NR, normal range; STP, serum total protein.